Shantae Lankford
Blog entry by Shantae Lankford
Innovative Depression Treatments
Many people with depression are struggling to find a treatment that works for them. Some suffer from an inability to respond to medication or experience uncontrollable adverse side effects.
The intrinsic health benefits of increased coverage of effective treatment are believed to be substantial (table 2). The discounted value for depression is $399 billion, and for anxiety disorders $169 billion.
Transcranial Magnetic Stimulation (TMS)
TMS uses magnetic fields to deliver brief pulses of electrical current to specific brain regions that are overactive in patients suffering from depression. The treatment is non-invasive and does not require anesthesia. It is also highly efficient and well-tolerated when compared to antidepressant drugs.
A person is able to receive TMS by sitting in a similar chair to the chair used by dentists. A trained technician places the device that has an electromagnetic coil against the frontal area of the head. The coil is able to pulse quickly and the person could hear a click or feel a tingling sensation on the scalp. Each magnetic pulse (measured in hertz or Hz) is known as a "pulseor pulse. The frequency of pulses can range from low (1 pulse every second) to high (10 per second).
The treatment isn't painful but the magnetic field affects the cells that are located in the outer layer. It depolarizes the cortical neurons and the transynaptic effect may affect deeper regions of brain that are involved in mood. For instance, higher-frequency TMS in the left DLPFC can stimulate mesolimbic neurons which regulate emotional responses.
TMS can be utilized as an adjunct to psychiatric drugs Some insurance plans cover the treatment. It is recommended to check with your insurance provider to determine what your plan covers.
In clinical trials, TMS produced significant and long-lasting improvements in depression pharmacological treatment symptoms over the placebo. In the TMS treatment program, a patient may undergo up to 30 sessions over the course of a few weeks. Patients with more severe depression may need more time to complete their treatment.
Some of the newer TMS treatments employ the use of a lower frequency pulse which is less likely to trigger side effects like seizures. While the method is still experimental, it is an alternative for patients who are not responding to psychotherapy or antidepressants.
Electroconvulsive Therapy (ECT)
ECT aids in restoring the brain's natural chemical balance. It is among the safest and most effective treatments for depression that can be used to treat other mental health issues such as schizophrenia.
The ECT procedure is performed in a hospital or an outpatient treatment center. The procedure is performed by medical experts. Before the procedure the general anaesthetic will be administered to ensure you don't feel any discomfort. The ECT team will connect monitoring equipment to monitor your heart rate, blood pressure, oxygen levels and brain waves. You will receive an anti-muscle relaxant to keep you relaxed and a mouthguard to guard your teeth. Two discs made of metal (bilateral ECT) or one disc (unilateral ECT) is placed on your head on either side or in the middle of your forehead. The anaesthetist then gives you an injection of medication that will put you to sleep.
You will wake up in the ECT room and a member of the ECT team will speak to you and answer any questions you may have. Before you can receive the treatment you will be asked to sign a consent form. It is recommended to have a friend or a relative present while you are learning about ECT treatment, as it may be difficult to take in all the information in one go. You should be given at minimum 24 hours to think about the treatment prior to having to make a decision.
During the procedure you will have brief seizures or fits lasting between 40 seconds and 2 min. The ECT doctor will alter the amount of electrical pulses you receive depending on the response you show. It is likely that you will have short sessions of ECT typically 6-12 sessions, two times a week.
There isn't a single theory on how ECT works however it appears to cause the release of certain chemicals that aid your brain cells communicate with each and each other. It also seems to alter the way parts of your brain develop.
ECT is effective in Treating depression Without antidepressants severe depressions, suicidal feeling, catatonia secondary depression and other psychiatric conditions. Research has shown that half of those who undergo ECT recover and stay healthy for one year or more. It is especially helpful for those who have not had a positive response to medication or other psychosocial treatments.
Deep brain stimulation (DBS)
Deep brain stimulation (DBS) is an operation that involves implanting electrodes in the brain. The electrodes are attached to a small device that sends electrical impulses to the region of your brain that regulates symptoms. The electrical pulses can help ease your symptoms and enhance your quality of life. DBS can treat many ailments including movement disorders such as Parkinson's or essential tremors and psychiatric conditions such as depression and obsessional-compulsive condition. It can also help reduce seizures in epilepsy sufferers. It is also used to treat severe pain caused by nerve and brain conditions.
DBS is an option to be used in conjunction with ECT or other treatments for TRD. It is important to remember that not all patients will benefit from DBS. Some patients don't experience any symptom improvement, and some may even experience a worsening symptoms of depression. This non-response is likely due to a mix of factors, including factors related to the patient like personality traits or psychiatric comorbidity, and factors that affect the clinical, such as inaccurate diagnosis or suboptimal DBS treatment.
Researchers employed a machine-learning algorithm to classify changes in LFPs observed during intraoperative DBS. The results revealed that changes in beta power were associated with the reduction of symptoms of depression. These results suggest DBS can be used as a predictor of antidepressant effects. This hypothesis needs to be confirmed by further research.
Although DBS is a well-established treatment for movement disorders and a rising number of psychiatric conditions but it is not widely recognized as a reliable treatment for depression. The FDA has approved DBS to decrease seizures in some people with hard-to-treat epilepsy, and studies are underway to determine whether DBS can be used to treat depression.
It is recommended to discuss the DBS procedure with a neurologist before undergoing it. Your neurologist will examine you and recommend the most appropriate treatment option for you. They will also inform you about the potential risks and benefits of DBS. You should also inquire about any tests or preparations you might need to take prior to the procedure. It is likely that you will require an imaging test, blood test and other tests before the procedure.
Cognitive behavioral therapy (CBT)
Cognitive behavioral therapy is one of the most popular kinds of psychotherapy and has been found to be efficient in a variety of different outcome studies. It is most often used as a standalone treatment but it may be used in conjunction with medication in some cases. CBT is a form of psychotherapy that assists you to develop a positive attitude towards the negative attitudes and thoughts that are contributing to your depression. It is based on the idea that the way you think about and react to situations is more significant than the actual situation. It is an active type of psychotherapy which focuses on solving problems by identifying and modifying unhelpful thinking patterns and identifying thoughts that are not adapted to your needs.
The aim of cbt treatment for depression is to help you become your own therapy by helping you understand and change the ways you think and behave. It employs exercises and home work in sessions and outside of sessions to help you learn new skills. CBT is focused on current issues and problems, not previous experiences and their root causes. It is necessary to know some details about your past to be able to address and understand problems that are currently affecting you.
CBT is a short-term therapy that typically lasts 6 to 20 sessions. It is an empirically grounded therapy, and its duration is guided by whether or not you are meeting the goals set at the beginning of therapy. It is an active therapy and requires a strong level of commitment and dedication on your part.
There are many other types of cognitive behavioral therapies that could be beneficial for you, including acceptance and commitment therapy, which teaches you to take positive actions even when you are experiencing negative emotions or thoughts and dialectical behavior therapy designed to tackle self-injury and suicidal thoughts that are persistent and interpersonal psychotherapy, which is aimed at resolving relationships that contribute to major depression treatment.
There are a lot of exciting new treatments on the horizon which promise to revolutionize treatment for those suffering from treating depression without antidepressants. Some treatments are already available. For instance, deep brain stimulation. A surgeon inserts electrodes in your brain to send impulses that alter the electric activity that causes your symptoms. There are many other advances in the research phase, like customized treatment for depression. This could eliminate the need to trial and error to find the best natural treatment for anxiety and depression treatment for you.